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The lactose permease of Escherichia coli (LacY), a model for the major facilitator superfamily, catalyzes the symport of a galactopyranoside and an H+ across the membrane by a mechanism in which the sugar-binding site in the middle of the protein becomes alternately accessible to either side of the membrane. However, all X-ray structures thus far show LacY in an inward-facing conformation with

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Ivy Bridge is the codename for the "third generation" of the Intel Core processors (Core i7, i5, i3).Ivy Bridge is a die shrink to 22 nanometer manufacturing process based on the 32 nanometer Sandy Bridge ("second generation" of Intel Core)—see tick–tock model.

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